|
|
| Acne Information |
|
|
Accutane Side Effects: Should Depression Be A Concern?
Medical professionals and acne-pestered adolescents have no doubts about the effectiveness of the severe acne drug isotretinoin. It's the looming possibility of side effects such as depression and fetal damage that makes people uneasy when considering using this medication. Accutane (isotretinoin) is one of Hoffman-LaRoche's most popular and controversial pharmaceuticals. This week, a study published in the Archives of Dermatology vindicated isotretinoin from causing depression. In this report, Christina Y. Chia, MD, from Saint Louis University Health Sciences Center, St. Louis, and colleagues examined whether patients with moderate to severe acne treated with isotretinoin experienced an increase in depressive symptoms compared with patients treated with a topical antibiotic, topical retinoid, and an oral antibiotic. Dr. Chia found that "The use of isotretinoin in the treatment of moderate-severe acne in adolescents did not increase depressive symptoms. On the contrary, our study shows that treatment of acne improves depressive symptoms". Five years earlier, in 2000, the isotretinoin-depression link still appeared misleading. That time, the Archives of Dermatology posted study, headed by Dr. Susan S. Jick, from the Boston University School of Medicine, which found no evidence that isotretinoin increases the risk for depression, suicide, or other psychiatric disorders. Even though isotretinoin finds ample support among dermatologists and psychiatrists, a host of parents, politicians and medical professionals hail isotretinoin as a medical misfortune. For instance, Dr. David J. Graham, the Associate Director for Science and Medicine in FDA's Office of Drug Safety, recently warned that Accutane should be taken off the market. And while there are few studies with any negative observations about isotretinoin, Dr. Douglas Bremner's research at of the Emory University School of Medicine has linked isotretinoin treatment with changes in brain function. At the conclusion of this study, published in the American Journal of Psychiatry, Dr. Bremner concurred with Dr. Graham's view that isotretinoin proves too dangerous for human use. Dr. Bremner explains that to invoke depression, isotretinoin must influence the brain. During the investigation, brain function of the subjects was measured using positron emission tomography (PET) before and after four months of treatment with isotretinoin. Isotretinoin treatment was associated with decreased brain metabolism in the orbitofrontal cortex- the area of the brain known to mediate symptoms of depression. Yet, there were no differences in severity of depressive symptoms between the isotretinoin and antibiotic treatment groups before or after treatment. The pessimistic effects of isotretinoin also caught the attention of Diane K. Wysowski PhD. Dr. Wysowski noted that in June 2000, isotretinoin ranked among the top 10 drugs linked to depression and suicide attempts in the FDA's Adverse Event Reporting System database. In 2001, Dr. Wysowski examined isotretinoin's depression inducing potential and posted her findings in the Journal of the American Academy of Dermatology. Dr. Wysowski concluded that more studies of isotretinoin are needed. She also advised patients and their parents to immediately report mood swings and symptoms that are suggestive of depression such as sadness, crying, loss of appetite, unusual fatigue, withdrawal, and inability to concentrate to their prescribing physician. These protective measures can avoid more serious side effects and permit appropriate treatment, including consideration of drug discontinuation and referral for psychiatric care. While dissension among researchers still exists about whether or not isotretinoin causes depression, one idea most of them can agree on is that more research on the side effects of isotretinoin are desirable. If you are not in the mood for being an isotretinoin guinea pig, Geoffrey Redmond MD, author of The Good News about Women's Hormones, suggests using hormone therapy and/or using Retin-A if isotretinoin seems too chancy for you. Health author and Stanford University graduate Naweko San-Joyz lovingly writes from her home in San Diego. Her works include "Acne Messages: Crack the code of your zits and say goodbye to acne" (ISBN: 0974912204) and the upcoming work "Skinny Fat Chicks, Why we're still not getting this dieting thing" (ISBN: 0974912212) for release in June of 2005. For useful acne self-help articles visit http://www.Noixia.com
Latest Acne News:Warning: MagpieRSS: Failed to fetch http://news.search.yahoo.com/news/rss?ei=UTF-8&p=acne&eo=UTF-8 (HTTP Response: HTTP/1.1 999 Unable to process request at this time -- error 999 ) in /home/.hellodolly/jsteiner64/acnearticles.org/magpierss/rss_fetch.inc on line 238 Site: Warning: Invalid argument supplied for foreach() in /home/.hellodolly/jsteiner64/acnearticles.org/inc/ads-body.inc on line 35 Site: Acne - Google News Study Outlines Teens' Preferences And Trade-offs For Freedom From Acne - Science Daily (press release)
|
|
|
|
RELATED ARTICLES
Adult Acne Treatment ? Simple Solutions Are you one of the millions of adults who have acne? Many adults are dealing with acne, the first signs of wrinkles and grey hair all at the same time ? talk about physical and emotional tolls. Life just seems too unfair at times. Fortunately, there are some simple solutions for treating acne. Really. You don't have to live with it. Silver Bullet for Acne? - I Dont Think So! I read a report recently discussing the success of the project to sequence the genome of the bacteria that is said to cause acne, Propionibacterium acnes, and how this may lead to new ways to treat Acne. Acne Program ? Step 9 Protein and Other Food to Eat Eating the right kind of food is what can give you a strong immune system and help you prevent sickness and all kinds of skin blemishes including acne. Acne Program ? An Introduction Acne is the most common skin disorder. Over 10% of Americans age 25 ? 44 have acne. Over 85% Americans age 12 ? 25 will have acne at one time or the other. An Acne Home Remedy Does Exist, Will It Work For You? Have you tried an acne home remedy? There are an amazing amount of products that are probably sitting in your kitchen right now, just waiting for you to put them on your face! You might be surprised at how helpful these acne home remedies can be. An acne home remedy may be more effective than you thought. Acne Prevention Tips Preventing acne is an extremely difficult thing to do. There really isn't a cure for it, yet it drags yourself esteem way down. So just what can an acne suffer do to help minimize breakouts? Here are some basic tips to help control your condition. Acne & Wrinkles at My Age? Puberty brought bouts of acne. In your 20s, finding Mr. or Mrs. Right was of chief consequence. When the 30s hit, you worked to raise little Johnnie or Suzie to be a model kid. Now that your hitting the fabulous 40s, you should be coasting through life, right. Well, why are you suddenly dealing with the cosmetic double whammy of acne and wrinkles? Even your insurance company figures that you should have gotten rid of acne by the age of 25. Is Milk Giving You the Zits? A study published in the February 2005 edition of the Journal of the American Academy of Dermatology re-ignites the acne diet controversy. The study's director, Clement A. Adebamowo, MD, and his team reported finding a positive association between acne and milk consumption. Accutane Side Effects: Should Depression Be A Concern? Medical professionals and acne-pestered adolescents have no doubts about the effectiveness of the severe acne drug isotretinoin. It's the looming possibility of side effects such as depression and fetal damage that makes people uneasy when considering using this medication. Acne and Skin Problem Myths Debunked Isn't skin a wonderful thing to have? Acne Scars ? Getting Rid of Bad Memories! Acne scars can often be the final reminder of a bad time in the life of a person's skin. Though acne is one of the most common skin disorders, most former patients feel no need to display their scars like war wounds from a hard won battle, and once sufferers have achieved the clear skin they have longed for so long, they move swiftly into a new fight ? how to remove, or at least lessen, their acne scars. Your Guide To Acne Skin Care Contrary to popular belief, acne is not caused by dirty pores or eating chocolate. Acne is actually caused by overactive sebaceous glands. Hormones in you body cause acne to appear. Acne is extremely common in people ages 12-24, when our hormones are very active due to puberty, but many people continue to have acne outbreaks throughout their lives. Acne can show up on the face, neck, chest, back, and shoulders. While it is not life threatening, acne can cause scarring and emotional distress to those that suffer from it. This is why acne skin care is so important. Acne Can Be A Problem At Any Age Adult, teenage and baby acne have something in common; no one likes the problem. Adult, teenage and baby acne problems are surrounded by myths. Take Advantage of Natural Acne Treatments Let's face it. Nobody is really immune to having acne from time to time. Don't blame your French fries. Don't blame your Hershey's bar. Don't blame yourself for not being able to wash your face enough. Don't blame being overworked. Acne does not happen because of those. Acne is caused by some imbalances in our body and internal impurities. This is the main reason to the imperative knowledge that the way to really get rid of acne is through internal cleansing. Acne Treatment Acne is an annoying skin condition that affects people of every age, gender, and race. The scientific name for the condition is acne vulgaris because acne usually strikes in plainly visible locations such as the face, neck, chest and back. Acne is an age old problem that has likely been plaguing people for centuries. But there are numerous treatment methods available for this bothersome condition. Read on to learn more about acne, and what you can do to treat it. Oily Skin Care Can Treat Acne-prone, Shiny, Oily Skin Oily skin is not only shiny, dull-colored, and coarse, it is also acne-prone, which means that a host of more serious problems can develop: blackheads, whiteheads, enlarged pores, redness, and potential scarring. If your skin is oily or you have combination skin, take control with oily skin care before the trouble escalates. We all want to have beautiful, clear skin. Colon Cleaning May Help Acne Sufferers Many doctors and alternative medicine practitioners believe that one essential component of achieving overall bodily health is having a colon that is clean and free of the toxins that can build up over time. Many of these same doctors and alternative medicine practitioners believe that one of the benefits of colon cleansing is the improvement of acne conditions. Acne ? A Clean Face ? First Step In A 12 Step Program For those that need more than a special cream like Scotty's Face Cream, then you need to work harder to get rid of acne. Since acne is a condition that occurs from within your body and exhibits on the outside of your body, you need to, Birth Control Pill for Acne There are quite a few prescription medications used to combat acne, but one of the most frequent choices for women is the use of a birth control pill for acne. This approach can be used with teenagers as well as adult women, but if you're a guy, you are out of luck. Using the birth control pill for acne on a man is a recipe for disaster. The female hormones would wreak havoc on a man's system. Acne Medications - Natural Adult Acne Treatments Adult acne - why must we suffer aging skin AND acne??
|
| Home | Site Map | Resource Links | Contact Us |
| © 2006 |
